Hard PVC - dialysis paper blister packaging machines are widely used in the pharmaceutical industry, particularly for sterile preparations and high-requirement drug packaging.
Its core purpose can be summarized as: providing a safe, reliable, high-barrier, and easy-to-use packaging form for drugs (especially sterile drugs) that are highly sensitive to moisture, oxygen, and microbial intrusion.
I. Core Packaging Form and Structure
Understanding this packaging form is key to understanding its purpose:
- Rigid PVC (Polyvinyl Chloride): Forms a transparent "blister" or "bubble" for carrying pharmaceuticals. It has good formability, transparency, and a certain degree of rigidity.
- Dialysis Paper: Seals the back of the PVC blister as a cap material. This material has key characteristics:
- High Microbial Barrier: Effectively blocks the intrusion of bacteria, mold, and other microorganisms, ensuring the sterility of the internal pharmaceuticals.
- Excellent breathability: Allows sterilization media such as ethylene oxide (EO) or vapor to penetrate for final sterilization of the packaged product while simultaneously blocking microorganisms.
- Tear-resistant and fiber-shedding resistant: Strong and durable, it does not produce fiber shavings like ordinary paper.
This structure, with one side being transparent rigid plastic and the other porous paper, perfectly balances the needs for product visibility, ease of use, and sterile safety.
II. Main Uses and Applicable Product Types
This packaging machine is specifically designed for the final packaging of the following types of pharmaceuticals:
1. Sterile Surgical Implants and Instruments
- Specific Products: Orthopedic implants (such as artificial joints, bone plates, screws), cardiovascular stents, surgical sutures, artificial lenses, neurosurgical implants, etc.
- Purpose: To ensure that these products, which are implanted directly into the human body, remain absolutely sterile during transportation and storage until they are opened and used by healthcare professionals in the operating room.
2. Pharmaceuticals and Medical Devices Requiring Terminal Sterilization
- Specific Products: Some injectable medications, pre-filled syringes, scalpel blades, catheters, cotton swabs, gauze pads, etc.
- Applications: After packaging, the entire packaging unit can undergo a final sterilization process (such as ethylene oxide sterilization or irradiation sterilization). Dialysis paper allows the sterilizing agent to penetrate while maintaining a durable sterile barrier.
3. Pharmaceuticals Highly Sensitive to Moisture and Oxygen
- Specific Products: Certain expensive biological agents, lyophilized powder injections, and highly hygroscopic oral medications.
- Applications: Although dialysis paper itself is breathable, rigid PVC blister packs provide good moisture and oxygen barrier protection. For products with higher requirements, composite films (such as PVC/PE/PVDC) can be used to enhance barrier properties, while still using dialysis paper as an easy-to-tear cap material to balance barrier and sterilization/breathability requirements.
4. Medicines Requiring High-Level Anti-counterfeiting and Tamper-proofing
- Purpose: Blister packaging itself possesses a certain degree of tamper-proofing; once torn, it cannot be restored. Combined with serialization, QR code, and other traceability systems, this packaging method can effectively prevent counterfeit and substandard products from entering the market.
III. Specific Functions of Packaging Machines in Achieving These Purposes
A rigid PVC/dialysis paper blister packaging machine achieves the above purposes through the following process:
- PVC Sheet Heating: Rolls of rigid PVC sheets are softened by a heating station, making them malleable.
- Blister Forming: Blisters of a specified shape and depth are formed on the softened PVC sheet using compressed air or die stamping.
- Product Filling: Medicines, medical devices, and other products are automatically or manually placed into the formed blister packs.
- Cover Sealing: Rolls of dialysis paper are placed over the filled PVC blister packs and heat-sealed under specific temperature, pressure, and time conditions to form a strong, airtight seal.
- Cutting and Coding: Cuts the sealed large sheets into individual packaging units (e.g., single blister packs, single rows, or specific combinations), and simultaneously prints information such as production date, batch number, and expiration date.
- Online Inspection (Optional but Important): Integrates a vision inspection system to automatically detect whether the blister pack is intact, whether the product is missing, and whether the seal is tight, ensuring that every package is flawless.
Summary
In conclusion, the core purpose of the **rigid PVC-dialysis paper blister packaging machine** is to create an ultimate packaging solution for pharmaceuticals and medical devices with stringent requirements for sterility, moisture resistance, and oxygen control, combining "high protection," "ease of use," and "production feasibility."
It is not merely a simple "machine for packing things," but a crucial production link that ensures patient medication safety and maintains drug efficacy and stability. It is an indispensable piece of equipment in the modern pharmaceutical industry, especially in the fields of high-end formulations and sterile medical devices.